o2h group seeds new ideas in  science, technology and green innovation. We work across boundaries and take a collaborative and shared approach to innovation, and therefore we co-invest, co-create and co-execute to bring these ideas to life.   o2h group is organised into 6 symbiotic verticals;  o2h ventures,  o2h discovery, o2h therapeutics, o2h technology, o2h co-work, and o2h community.

Post : Research Associate / Senior Research Associate – ADME

Job description
•  Performing all ADME assays
•  Method development and data collection by LC-MS/MS, and other modalities (Absorbance/Fluorescence)
•  Supporting in new assay development for ADME activities
•  To analyse data from enzyme activities (GraphPad Prism, MS-excel) & MS data (Sciex)
•  Compiling reports and interfacing with collaborators
•  Coordinating with third-party collaborators for PK study (animal models)
•  Conducting day-to-day testing and profiling of compounds in cells/protein-based assays
•  Drafting reports, documenting experiments and proficiently presenting results within the lab and in various forums/meetings as and when needed
•  Work closely with other biology group members involved in screening, cell biology, protein biology and ADME, offering integrated drug discovery support alongside chemistry for multiple client-based projects
•  Contributing in group activities (like ordering, stocking and follow-ups etc.)

Candidate Profile
• M.Sc / M.Pharma (Microbiology/Biotechnology)
•  1-4 years of working experience with LC-MS/MS, HPLC, bio-analytical studies etc.
•  An excellent understanding and knowledge of laboratory tools, techniques, methods, and underlying principles
•  Hands-on/practical exposure in general biotech laboratory equipment (cell-culture lab, in-vitro and ADME lab)
•  Excellent theoretical understanding and practical work experience with cell culture techniques (established cell lines), ADME assays (microsomal stability, plasma stability, solubility, permeability, CYP inhibition assays, plasma protein binding assays etc.)
•  An ability to overcome technical challenges and exercise sound judgment under pressure 
•  High self-motivation to initiate projects and work independently under aggressive deadlines
•  A strong technical knowledge with exceptional attention to detail
•  An excellent personal rapport and an ability to engender trust and respect
•  An ability to work well as part of a small focussed team and build relationships
•  An ability to multitask, recognize problems and provide input to solutions
•  An exceptional communication skill and an ease in interaction with all stakeholders 
•  An infectious enthusiasm for life, work and making a difference to the world in which we live
•  A bright, friendly, flexible personality with agility to switch between different skill sets
•  An exceptional organisational skill that thrives working in a fast-paced and vibrant team environment
•  Positivity, focus and a winning mentality allied with kindness
•  Curiosity, energy, creativity, and bravery with a strong desire to help to build the o2h culture

Additional Information
Experience : 1-4 years
Qualification : M.Sc / M.Pharma
Location : Changodar, Ahmedabad
End Date : 20th July 2024

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